Cleveland Browns Stadium will play host to Monday's Round 6 NFL game between Cleveland Browns and San Francisco 49ers. The game kicks off at 4:00 am with San Francisco 49ers heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Cleveland Browns vs. San Francisco 49ers game and give you our free tips and bets.

When: Monday October 16, 2023 at 4:00 am

Where: Cleveland Browns Stadium

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Cleveland Browns vs San Francisco 49ers Odds

Cleveland Browns vs San Francisco 49ers Preview

San Francisco is easily the best team in the league and the word “team” is the most important part of that statement, they are getting contributions from all over the roster.

Brock Purdy is happy to play Robin to the multiple Batman impersonators on the offence with Christian McCaffrey, Deebo Samuel, George Kittle and Brandon Aiyuk.

On defence it’s the dynamic duo of Nick Bosa and Fred Warner leading the way with the rest of the squad playing a strong role in the supporting cast.

Bottom line for Cleveland is that the Browns have been a team incredibly reliant on their defence and right now they just don’t seem to be able to compete with the 49ers.

In their two wins they have given up a grand total of six points and there is a chance the 49ers cover that total on their first possession.

Add in the major uncertainty surrounding Deshaun Watson and his injured shoulder, with the likely replacement being the underwhelming PJ Walker, and the 49ers defence could be in for a field day as well.

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Cleveland Browns vs San Francisco 49ers Tip