Levi's Stadium will play host to Tuesday's Round 17 NFL game between San Francisco 49ers and Detroit Lions. The game kicks off at 12:15 pm with Detroit Lions heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the San Francisco 49ers vs. Detroit Lions game and give you our free tips and bets.

When: Tuesday December 31, 2024 at 12:15 pm

Where: Levi's Stadium

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San Francisco 49ers vs Detroit Lions Odds

San Francisco 49ers vs Detroit Lions Preview

A second loss this season did not ruin the Detroit Lions season as they went into the cold in Chicago and dominated the Bears last week.

Now if fate goes their way (for once), they could book a weekend off in January and make sure that the next time they have to leave their home will be for the Super Bowl in New Orleans.

Even if they do not have the opportunity to secure home field advantage, they will have plenty to motivate them against a banged up 49ers side.

If nothing else there will be some comfort having lost the NFC Championship in this stadium back in January.

Back in May this looked like a late season blockbuster, now it looks like a pretty big mismatch.

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San Francisco 49ers vs Detroit Lions Tip