Old Trafford will play host to Friday's Round 21 EPL game between Manchester United and Southampton. The game kicks off at 7:00 am with Manchester United heading into the game as favourites with the bookmakers. Continue reading for our in-depth preview of the Manchester United vs. Southampton game and give you our free tips and bets.

When: Friday January 17, 2025 at 7:00 am

Where: Old Trafford

Bet 💰: Bet On This Match HERE

Manchester United vs Southampton Odds

Manchester United vs Southampton Preview

It was the win that Manchester United needed in the worst possible way, knocking out Arsenal in the FA Cup on penalties.

Now they have a perfect chance to build on that result against the Premier League’s worst team as Ruben Amorim’s build takes shape.

The Saints might have defeated Swansea on the weekend but when it comes to playing against opponents in (and above) their weight class, they are horrifically overmatched.

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Manchester United vs Southampton Tip