Australia’s Marinko Matosevic has fallen to South African fourth seed Kevin Anderson in the quarter-finals of the ATP Delray Beach Open in a rematch of the 2012 final.

Anderson fired 10 aces and connected on 61 per cent of his first serves in a 6-7 (3-7) 6-3 6-3 victory over his 55th-ranked rival, who had nine aces but also six double-faults and only a 49 per cent first-serve success rate in Florida on Friday.

Seeking his second Delray Beach title in three years and third ATP career crown, Anderson advanced to a Saturday clash with US qualifier Steve Johnson, who eliminated Spanish sixth seed Feliciano Lopez 6-3 6-2 in 73 minutes.

Anderson, who lives nearby, surrendered only one break over two hours and 23 minutes in improving to 12-3 all time at Delray Beach and 3-0 against Matosevic.

“I’ve played him a couple times before and it’s a battle each time,” Anderson said. “I just hung in there and finally got that breakthrough in the second set. It was gusty and it was tough to get a rhythm.

“I’m in the semis and that’s a great feeling.”

Anderson’s only other title came in 2011 on home soil in Johannesburg.

In later quarter-finals, US second seed John Isner will meet American qualifier Rhyne Williams and Croatian seventh seed Marin Cilic will face Russia’s Teymuraz Gabashvili.