Defending champion Andy Murray was ousted from the US Open on Thursday, falling to Swiss ninth seed Stanislas Wawrinka 6-4 6-3 6-2 in a quarter-final shocker at Arthur Ashe Stadium.

Wawrinka reached his first Grand Slam semi-final by stunning the reigning Olympic and Wimbledon champion, booking a Saturday last-four date against either Russian 21st seed Mikhail Youzhny or world number one Novak Djokovic.

Spanish second seed Rafael Nadal and French eighth seed Richard Gasquet will meet in Saturday’s other semi-final.